Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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IDC Breast Radvanyi Cluster Number 59 (137 genes) This page contains all miRNA mediated regulation and functional enrichment for IDC Breast Radvanyi cluster number 59. Information about breast cancer can be found on Wikipedia, and further information about the "IDC Breast Radvanyi" dataset can be found in Radvanyi et al., 2005. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan hsa-mir-1469 zzz999 zzz999 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0000022 mitotic spindle elongation 2 GO:0000070 mitotic sister chromatid segregation 9 GO:0000075 cell cycle checkpoint 18 GO:0000082 G1/S transition of mitotic cell cycle 12 GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 4 GO:0000084 S phase of mitotic cell cycle 11 GO:0000086 G2/M transition of mitotic cell cycle 6 GO:0000087 M phase of mitotic cell cycle 39 GO:0000216 M/G1 transition of mitotic cell cycle 6 GO:0000226 microtubule cytoskeleton organization 14 GO:0000236 mitotic prometaphase 15 GO:0000278 mitotic cell cycle 53 GO:0000279 M phase 48 GO:0000280 nuclear division 37 GO:0000819 sister chromatid segregation 9 GO:0000910 cytokinesis 8 GO:0006259 DNA metabolic process 29 GO:0006260 DNA replication 13 GO:0006261 DNA-dependent DNA replication 9 GO:0006270 DNA-dependent DNA replication initiation 6 GO:0006271 DNA strand elongation involved in DNA replication 6 GO:0006281 DNA repair 13 GO:0006310 DNA recombination 8 GO:0006323 DNA packaging 14 GO:0006333 chromatin assembly or disassembly 9 GO:0006334 nucleosome assembly 8 GO:0006336 DNA replication-independent nucleosome assembly 5 GO:0006338 chromatin remodeling 6 GO:0006511 ubiquitin-dependent protein catabolic process 10 GO:0006974 response to DNA damage stimulus 14 GO:0006996 organelle organization 54 GO:0007010 cytoskeleton organization 16 GO:0007017 microtubule-based process 20 GO:0007018 microtubule-based movement 8 GO:0007049 cell cycle 65 GO:0007051 spindle organization 8 GO:0007052 mitotic spindle organization 4 GO:0007059 chromosome segregation 15 GO:0007067 mitosis 37 GO:0007076 mitotic chromosome condensation 3 GO:0007079 mitotic chromosome movement towards spindle pole 2 GO:0007080 mitotic metaphase plate congression 3 GO:0007088 regulation of mitosis 8 GO:0007094 mitotic cell cycle spindle assembly checkpoint 5 GO:0007096 regulation of exit from mitosis 3 GO:0007346 regulation of mitotic cell cycle 14 GO:0008283 cell proliferation 25 GO:0008608 attachment of spindle microtubules to kinetochore 3 GO:0010458 exit from mitosis 4 GO:0010498 proteasomal protein catabolic process 10 GO:0010564 regulation of cell cycle process 26 GO:0016043 cellular component organization 66 GO:0019941 modification-dependent protein catabolic process 10 GO:0022402 cell cycle process 62 GO:0022403 cell cycle phase 59 GO:0022616 DNA strand elongation 6 GO:0030261 chromosome condensation 5 GO:0031055 chromatin remodeling at centromere 6 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 9 GO:0031497 chromatin assembly 9 GO:0031577 spindle checkpoint 8 GO:0033554 cellular response to stress 19 GO:0034080 CenH3-containing nucleosome assembly at centromere 5 GO:0034508 centromere complex assembly 3 GO:0034621 cellular macromolecular complex subunit organization 20 GO:0034622 cellular macromolecular complex assembly 16 GO:0034724 DNA replication-independent nucleosome organization 5 GO:0034728 nucleosome organization 8 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 10 GO:0043632 modification-dependent macromolecule catabolic process 10 GO:0043933 macromolecular complex subunit organization 23 GO:0044257 cellular protein catabolic process 10 GO:0045842 positive regulation of mitotic metaphase/anaphase transition 2 GO:0048285 organelle fission 37 GO:0050000 chromosome localization 5 GO:0051231 spindle elongation 2 GO:0051276 chromosome organization 24 GO:0051301 cell division 37 GO:0051303 establishment of chromosome localization 5 GO:0051305 chromosome movement towards spindle pole 2 GO:0051310 metaphase plate congression 3 GO:0051320 S phase 11 GO:0051325 interphase 18 GO:0051329 interphase of mitotic cell cycle 18 GO:0051340 regulation of ligase activity 7 GO:0051352 negative regulation of ligase activity 5 GO:0051438 regulation of ubiquitin-protein ligase activity 7 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5 GO:0051444 negative regulation of ubiquitin-protein ligase activity 5 GO:0051488 activation of anaphase-promoting complex activity 3 GO:0051603 proteolysis involved in cellular protein catabolic process 10 GO:0051640 organelle localization 7 GO:0051656 establishment of organelle localization 6 GO:0051726 regulation of cell cycle 28 GO:0051983 regulation of chromosome segregation 5 GO:0051984 positive regulation of chromosome segregation 2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 2 GO:0065004 protein-DNA complex assembly 10 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-1469 miRvestigator GO:0000022 mitotic spindle elongation 1 2 137 42 0.09242164 hsa-mir-1469 miRvestigator GO:0000070 mitotic sister chromatid segregation 2 9 137 42 0.559106 hsa-mir-1469 miRvestigator GO:0000075 cell cycle checkpoint 3 18 137 42 0.867494 hsa-mir-1469 miRvestigator GO:0000082 G1/S transition of mitotic cell cycle 3 12 137 42 0.5319907 hsa-mir-1469 miRvestigator GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 1 4 137 42 0.3593664 hsa-mir-1469 miRvestigator GO:0000084 S phase of mitotic cell cycle 2 11 137 42 0.7139871 hsa-mir-1469 miRvestigator GO:0000086 G2/M transition of mitotic cell cycle 1 6 137 42 0.598148 hsa-mir-1469 miRvestigator GO:0000087 M phase of mitotic cell cycle 6 39 137 42 0.9895286 hsa-mir-1469 miRvestigator GO:0000216 M/G1 transition of mitotic cell cycle 1 6 137 42 0.598148 hsa-mir-1469 miRvestigator GO:0000226 microtubule cytoskeleton organization 5 14 137 42 0.2259125 hsa-mir-1469 miRvestigator GO:0000236 mitotic prometaphase 0 15 137 42 0.9971567 hsa-mir-1469 miRvestigator GO:0000278 mitotic cell cycle 10 53 137 42 0.9867879 hsa-mir-1469 miRvestigator GO:0000279 M phase 10 48 137 42 0.9509591 hsa-mir-1469 miRvestigator GO:0000280 nuclear division 6 37 137 42 0.9810597 hsa-mir-1469 miRvestigator GO:0000819 sister chromatid segregation 2 9 137 42 0.559106 hsa-mir-1469 miRvestigator GO:0000910 cytokinesis 1 8 137 42 0.7656722 hsa-mir-1469 miRvestigator GO:0006259 DNA metabolic process 8 29 137 42 0.5635452 hsa-mir-1469 miRvestigator GO:0006260 DNA replication 3 13 137 42 0.6077012 hsa-mir-1469 miRvestigator GO:0006261 DNA-dependent DNA replication 2 9 137 42 0.559106 hsa-mir-1469 miRvestigator GO:0006270 DNA-dependent DNA replication initiation 1 6 137 42 0.598148 hsa-mir-1469 miRvestigator GO:0006271 DNA strand elongation involved in DNA replication 1 6 137 42 0.598148 hsa-mir-1469 miRvestigator GO:0006281 DNA repair 3 13 137 42 0.6077012 hsa-mir-1469 miRvestigator GO:0006310 DNA recombination 2 8 137 42 0.4662672 hsa-mir-1469 miRvestigator GO:0006323 DNA packaging 2 14 137 42 0.8653131 hsa-mir-1469 miRvestigator GO:0006333 chromatin assembly or disassembly 0 9 137 42 0.9672003 hsa-mir-1469 miRvestigator GO:0006334 nucleosome assembly 0 8 137 42 0.9513659 hsa-mir-1469 miRvestigator GO:0006336 DNA replication-independent nucleosome assembly 0 5 137 42 0.8448992 hsa-mir-1469 miRvestigator GO:0006338 chromatin remodeling 0 6 137 42 0.8942495 hsa-mir-1469 miRvestigator GO:0006511 ubiquitin-dependent protein catabolic process 3 10 137 42 0.3654501 hsa-mir-1469 miRvestigator GO:0006974 response to DNA damage stimulus 4 14 137 42 0.4370472 hsa-mir-1469 miRvestigator GO:0006996 organelle organization 11 54 137 42 0.9736594 hsa-mir-1469 miRvestigator GO:0007010 cytoskeleton organization 5 16 137 42 0.3565808 hsa-mir-1469 miRvestigator GO:0007017 microtubule-based process 6 20 137 42 0.4143511 hsa-mir-1469 miRvestigator GO:0007018 microtubule-based movement 1 8 137 42 0.7656722 hsa-mir-1469 miRvestigator GO:0007049 cell cycle 14 65 137 42 0.9785283 hsa-mir-1469 miRvestigator GO:0007051 spindle organization 4 8 137 42 0.05755565 hsa-mir-1469 miRvestigator GO:0007052 mitotic spindle organization 1 4 137 42 0.3593664 hsa-mir-1469 miRvestigator GO:0007059 chromosome segregation 3 15 137 42 0.7360007 hsa-mir-1469 miRvestigator GO:0007067 mitosis 6 37 137 42 0.9810597 hsa-mir-1469 miRvestigator GO:0007076 mitotic chromosome condensation 1 3 137 42 0.2224965 hsa-mir-1469 miRvestigator GO:0007079 mitotic chromosome movement towards spindle pole 0 2 137 42 0.520717 hsa-mir-1469 miRvestigator GO:0007080 mitotic metaphase plate congression 1 3 137 42 0.2224965 hsa-mir-1469 miRvestigator GO:0007088 regulation of mitosis 1 8 137 42 0.7656722 hsa-mir-1469 miRvestigator GO:0007094 mitotic cell cycle spindle assembly checkpoint 1 5 137 42 0.4869744 hsa-mir-1469 miRvestigator GO:0007096 regulation of exit from mitosis 1 3 137 42 0.2224965 hsa-mir-1469 miRvestigator GO:0007346 regulation of mitotic cell cycle 3 14 137 42 0.6759628 hsa-mir-1469 miRvestigator GO:0008283 cell proliferation 5 25 137 42 0.850863 hsa-mir-1469 miRvestigator GO:0008608 attachment of spindle microtubules to kinetochore 0 3 137 42 0.6698273 hsa-mir-1469 miRvestigator GO:0010458 exit from mitosis 1 4 137 42 0.3593664 hsa-mir-1469 miRvestigator GO:0010498 proteasomal protein catabolic process 3 10 137 42 0.3654501 hsa-mir-1469 miRvestigator GO:0010564 regulation of cell cycle process 6 26 137 42 0.7529136 hsa-mir-1469 miRvestigator GO:0016043 cellular component organization 14 66 137 42 0.9837169 hsa-mir-1469 miRvestigator GO:0019941 modification-dependent protein catabolic process 3 10 137 42 0.3654501 hsa-mir-1469 miRvestigator GO:0022402 cell cycle process 14 62 137 42 0.9540496 hsa-mir-1469 miRvestigator GO:0022403 cell cycle phase 13 59 137 42 0.9579317 hsa-mir-1469 miRvestigator GO:0022616 DNA strand elongation 1 6 137 42 0.598148 hsa-mir-1469 miRvestigator GO:0030261 chromosome condensation 2 5 137 42 0.1679544 hsa-mir-1469 miRvestigator GO:0031055 chromatin remodeling at centromere 0 6 137 42 0.8942495 hsa-mir-1469 miRvestigator GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 2 9 137 42 0.559106 hsa-mir-1469 miRvestigator GO:0031497 chromatin assembly 0 9 137 42 0.9672003 hsa-mir-1469 miRvestigator GO:0031577 spindle checkpoint 1 8 137 42 0.7656722 hsa-mir-1469 miRvestigator GO:0033554 cellular response to stress 4 19 137 42 0.7566203 hsa-mir-1469 miRvestigator GO:0034080 CenH3-containing nucleosome assembly at centromere 0 5 137 42 0.8448992 hsa-mir-1469 miRvestigator GO:0034508 centromere complex assembly 0 3 137 42 0.6698273 hsa-mir-1469 miRvestigator GO:0034621 cellular macromolecular complex subunit organization 2 20 137 42 0.9775897 hsa-mir-1469 miRvestigator GO:0034622 cellular macromolecular complex assembly 2 16 137 42 0.9230186 hsa-mir-1469 miRvestigator GO:0034724 DNA replication-independent nucleosome organization 0 5 137 42 0.8448992 hsa-mir-1469 miRvestigator GO:0034728 nucleosome organization 0 8 137 42 0.9513659 hsa-mir-1469 miRvestigator GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 3 10 137 42 0.3654501 hsa-mir-1469 miRvestigator GO:0043632 modification-dependent macromolecule catabolic process 3 10 137 42 0.3654501 hsa-mir-1469 miRvestigator GO:0043933 macromolecular complex subunit organization 3 23 137 42 0.9661061 hsa-mir-1469 miRvestigator GO:0044257 cellular protein catabolic process 3 10 137 42 0.3654501 hsa-mir-1469 miRvestigator GO:0045842 positive regulation of mitotic metaphase/anaphase transition 0 2 137 42 0.520717 hsa-mir-1469 miRvestigator GO:0048285 organelle fission 6 37 137 42 0.9810597 hsa-mir-1469 miRvestigator GO:0050000 chromosome localization 1 5 137 42 0.4869744 hsa-mir-1469 miRvestigator GO:0051231 spindle elongation 1 2 137 42 0.09242164 hsa-mir-1469 miRvestigator GO:0051276 chromosome organization 4 24 137 42 0.9220219 hsa-mir-1469 miRvestigator GO:0051301 cell division 8 37 137 42 0.8835047 hsa-mir-1469 miRvestigator GO:0051303 establishment of chromosome localization 1 5 137 42 0.4869744 hsa-mir-1469 miRvestigator GO:0051305 chromosome movement towards spindle pole 0 2 137 42 0.520717 hsa-mir-1469 miRvestigator GO:0051310 metaphase plate congression 1 3 137 42 0.2224965 hsa-mir-1469 miRvestigator GO:0051320 S phase 2 11 137 42 0.7139871 hsa-mir-1469 miRvestigator GO:0051325 interphase 4 18 137 42 0.7046055 hsa-mir-1469 miRvestigator GO:0051329 interphase of mitotic cell cycle 4 18 137 42 0.7046055 hsa-mir-1469 miRvestigator GO:0051340 regulation of ligase activity 2 7 137 42 0.3664656 hsa-mir-1469 miRvestigator GO:0051352 negative regulation of ligase activity 2 5 137 42 0.1679544 hsa-mir-1469 miRvestigator GO:0051438 regulation of ubiquitin-protein ligase activity 2 7 137 42 0.3664656 hsa-mir-1469 miRvestigator GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1 5 137 42 0.4869744 hsa-mir-1469 miRvestigator GO:0051444 negative regulation of ubiquitin-protein ligase activity 2 5 137 42 0.1679544 hsa-mir-1469 miRvestigator GO:0051488 activation of anaphase-promoting complex activity 1 3 137 42 0.2224965 hsa-mir-1469 miRvestigator GO:0051603 proteolysis involved in cellular protein catabolic process 3 10 137 42 0.3654501 hsa-mir-1469 miRvestigator GO:0051640 organelle localization 2 7 137 42 0.3664656 hsa-mir-1469 miRvestigator GO:0051656 establishment of organelle localization 1 6 137 42 0.598148 hsa-mir-1469 miRvestigator GO:0051726 regulation of cell cycle 7 28 137 42 0.6856038 hsa-mir-1469 miRvestigator GO:0051983 regulation of chromosome segregation 2 5 137 42 0.1679544 hsa-mir-1469 miRvestigator GO:0051984 positive regulation of chromosome segregation 0 2 137 42 0.520717 hsa-mir-1469 miRvestigator GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 0 2 137 42 0.520717 hsa-mir-1469 miRvestigator GO:0051988 regulation of attachment of spindle microtubules to kinetochore 0 2 137 42 0.520717 hsa-mir-1469 miRvestigator GO:0065004 protein-DNA complex assembly 0 10 137 42 0.9779627

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